PRODUCT SRARCH
Welcome to use the web search system, you can enter the product name or product CAS number to search product . If you have any questions or sugesstions, please contact us.
|
Cas No. |
Product name |
5142-23-4 |
NSC66389 |
more... |
|
1166227-08-2 |
A66 |
more... |
A66 is a potent and specific p110α inhibitor with IC50 of 32 nM, >100 fold selectivity for p110α over other class-I PI3K isoforms |
1217486-61-7 |
BYL719 |
more... |
BYL719 is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, and minimal effect on PI3Kβ/γ/δ. Phase 2 |
1246560-33-7 |
VS-5584 (SB2343) |
more... |
VS-5584 (SB2343) is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3Kα/β/δ/γ with IC50 of 3.4 nM and 2.6-21 nM, respectively |
1201438-56-3 |
IPI-145 (INK1197) |
more... |
IPI-145 (INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM, highly selective for PI3K δ/γ than other protein kinases. Phase 2 |
1009298-09-2 |
AZD8055 |
more... |
AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM with excellent selectivity (~1,000-fold) against PI3K isoforms and ATM/DNA-PK. Phase 1 |
870281-82-6 |
CAL-101 (Idelalisib, GS-1101) |
more... |
CAL-101 (Idelalisib, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM; shown to have 40- to 300-fold greater selectivity for p110δ thanp110α/β/γ, and 400- to 4000-... |
1173900-33-8 |
AZD6482 |
more... |
AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ. Phase 1 |
|
AZD6482(s) |
more... |
AZD6482(s) is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ |
1276105-89-5 |
CNX-1351 |
more... |
CNX-1351 is a selective covalent Inhibitor of PI3Kα. CNX-1351 was tested against all four of the class I PI3K enzymes α, β, γ, and δ. In an end point assay, CNX-1351 potently... |
|